Specimens
Specimen Inventory
A critical component of PPMI is the standardized, longitudinal collection of biospecimens. These include plasma, serum, blood, cerebrospinal fluid (CSF), DNA and RNA, and peripheral mononuclear blood cells (PBMCs).
PPMI samples are available for request only for biomarker verification studies. Review an inventory of available PPMI biospecimens below.
Please also see the Biomarker Dashboard (with link to dashboard) for information on biomarker data generated by PPMI. It details the associated projects and provides the number of participants with available biomarker data, categorized by cohort characteristics. See more information in Section 8.2 of the Data User Guide (with link to user guide). Also see a list of Ongoing Specimen Analysis (with link to Ongoing Specimen Analysis) in PPMI.
Interested in requesting biospecimens for other biomarker research? View our complimentary resources.
The tables below are an inventory of the number and type of biospecimen samples collected and currently available for analysis. Click here to download a PPMI PBMC Isolation overview.
All Biospecimens
| EVENT_ID | SC | BL | V01 | V02 | V03 | V04 | V05 | V06 | V07 | V08 | V09 | V10 | V11 | V12 | V13 | V14 | V15 | V16 | V17 | V18 | V19 | V20 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Months | SC | BL | 3 | 6 | 9 | 12 | 18 | 24 | 30 | 36 | 42 | 48 | 54 | 60 | 72 | 84 | 96 | 108 | 120 | 132 | 144 | 156 |
PD
| EVENT_ID | SC | BL | V01 | V02 | V03 | V04 | V05 | V06 | V07 | V08 | V09 | V10 | V11 | V12 | V13 | V14 | V15 | V16 | V17 | V18 | V19 | V20 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Months | SC | BL | 3 | 6 | 9 | 12 | 18 | 24 | 30 | 36 | 42 | 48 | 54 | 60 | 72 | 84 | 96 | 108 | 120 | 132 | 144 | 156 |
Prodromal
| EVENT_ID | SC | BL | V01 | V02 | V03 | V04 | V05 | V06 | V07 | V08 | V09 | V10 | V11 | V12 | V13 | V14 | V15 | V16 | V17 | V18 | V19 | V20 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Months | SC | BL | 3 | 6 | 9 | 12 | 18 | 24 | 30 | 36 | 42 | 48 | 54 | 60 | 72 | 84 | 96 | 108 | 120 | 132 | 144 | 156 |
Healthy Controls
| EVENT_ID | SC | BL | V01 | V02 | V03 | V04 | V05 | V06 | V07 | V08 | V09 | V10 | V11 | V12 | V13 | V14 | V15 | V16 | V17 | V18 | V19 | V20 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Months | SC | BL | 3 | 6 | 9 | 12 | 18 | 24 | 30 | 36 | 42 | 48 | 54 | 60 | 72 | 84 | 96 | 108 | 120 | 132 | 144 | 156 |
SWEDD
| EVENT_ID | SC | BL | V01 | V02 | V03 | V04 | V05 | V06 | V07 | V08 | V09 | V10 | V11 | V12 | V13 | V14 | V15 | V16 | V17 | V18 | V19 | V20 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Months | SC | BL | 3 | 6 | 9 | 12 | 18 | 24 | 30 | 36 | 42 | 48 | 54 | 60 | 72 | 84 | 96 | 108 | 120 | 132 | 144 | 156 |
Start the Specimen Request Process
Once you’ve understood the process outlined above, you’re ready to start to make a request. The link below will take you to the first step, registering on MJFF’s Grant Portal. You can view an instructional template for help in navigating the portal.
GO NOWResearch Funding for Specimen Studies
Researchers requesting biospecimens may also apply for funding from The Michael J. Fox Foundation (MJFF). The review processes for PPMI biospecimen access and MJFF funding of research are separate processes; approval for use of PPMI biospecimens does not guarantee MJFF funding. MJFF has identified Biomarkers as a priority funding area and will consider proposals from researchers who have been granted PPMI samples. Investigators interested in requesting funding from MJFF should indicate that in their Pre-Proposal.
Resources
Academic and industry investigators can apply for use of PPMI biospecimens to verify potential PD progression biomarkers.
Have a question on specimen inventory or request process? Check our Frequently Asked Questions.
The study’s data and biosample collection, storage and analysis methods have become field-wide standards.
PPMI enrolls and follows participants at around 50 international centers. View a list of PPMI clinical sites, site PIs and coordinators.